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CHARACTERISTIC CERVICAL CELL CHANGES
SQUAMOUS CELLS
*General
cytomegaly
most
often occurring in intermediate cells
*Cells
may enlarge to 70 microns in diameter or more
*Superficial
cells may be effected similarly but not as often
.
NUCLEAR CHARACTERISTICS
*Nuclei
>14 microns in diameter, about twice their normal size
*Nuclear
membrane folding and creasing may be more
frequent than cytomegaly
*Look
for longitudinal lines of chromatin within the nucleus
*Enlarged
nuclei usually appear bland with
prominent chromocenters
*Nuclear clearing (wide
pale clear space around the nucleus) may be seen,
especially in association
with radiation and chemotherapy
*Occasional
"masquerading" dysplastic nucleus may be found
*Sometimes
overall changes may mimic mild dysplasia
.
CYTOPLASMIC FEATURES
*Enlarged,
pale, and often polychromatic
*Vacuolization
may be quite pronounced, especially around
the nucleus
*Conspicuous
fibrils
(thin
lines that ring the nucleus) may be observed
*Bizarre
shapes may be found, some with psuedopod-like projections
(they are more frequently
associated with radiation and chemotherapy)
*PMN’s
may be ingested in vacuoles
.
Cerebral
Folate Deficiency
Autism
and Cerebral Folate Deficiency
Role
of Folic Acid in Neurological and Psychiatric Diseases
Folate
and Depression
Folic
Acid Deficiency and HPV
Folic
Acid Enzymes Inhibit UV Sun Damage
Age-Associated
Changes in the Metabolism of Vitamin B(12) and Folic Acid
Stroke
Rates Take Major Dive After Folate Fortification of Grain
Effect
of Folic Acid on Endothelial Function Following Acute Myocardial Infarction
Efficacy
of Folic Acid Supplementation in Stroke Prevention
.Niacin
(Vitamin B3) Improves HDL Levels
Plasma
Folate, Vitamin B6, vitamin B12, Homocysteine, and Risk of Breast Cancer
Birth Defects
Cerebral
Folate Deficiency
Report of the Effects on
Children with Brain Deficiency
Endothelial
Function in Newborn Infants is Related to Folate Levels and Birth Weight
Folic
Acid Deficiency and Birth Defects- It's Not Just about NTD's
Folic
Acid Blood Levels Falling In Young Women, Even After Fortification
See CDC's
MMWR-2007-Full
Report
Can
You Pass the Folic Acid Quiz?
"Point
4 the Future" Campaign
A Folic Acid Awareness Program
Aimed at Increasing Folic Acid
Intake Among College WomenTo
Protect Future Generations
Brain Function
Alzheimer's
Disease and Folic Acid
.Folic
Acid, DNA, and Alzheimer's Disease
Homocysteine
and B Vitamins Relate to Brain Volume and White-Matter
Changes in Geriatric Patients
with Psychiatric Disorders
Folate
and Cognitive Function
B
Vitamin Deficiency in Neurological and Psychiatric Disorders
..Treatment
of Depression: Time to Consider Folic Acid and B12
Cervical Cancer
Diet
and Premalignant Lesions of the Cervix:
Protective Role of Folate,
Riboflavin, Thiamin, and Vitamin B12
Folate
Deficiency and HPV Infection
Excerpt
from The Art of Cytology
Back to:
Normal
Cervical Cells / Hormone Effect /
The
Color Diet / The
Art of Cytology
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